The signs associated with a bone tumor are often nonspecific and at least initially, difficult to differentiate from arthritis or a potential sprain or strain after activity. Tumors in the limbs often cause various degrees of lameness and pain, and a firm swelling may become evident as the tumor size increases. It is common for pain to be intermittent initially, and it may improve initially with pain medications prescribed by your veterinarian. As the degree of discomfort increases, it can cause other signs such as irritability, aggression, loss of appetite, weight loss, sleeplessness, or reluctance to exercise. Some dogs may actually present to the veterinarian as a result of a fracture, due to weakening of the affected bone. Other clinical signs may vary, depending on the primary site and involvement of underlying structures.
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